Activated carbon is a black powder or granular amorphous carbon, mainly composed of elements such as oxygen and hydrogen in addition to carbon. Activated carbon is a porous carbon with low packing density and large specific surface area due to the irregular arrangement of microcrystalline carbon and the presence of pores between cross connections, which can cause carbon defects during activation.
Medicinal activated carbon is made from materials such as wood and charcoal, and is produced using two activation processes, chemical or physical, and refined into powdered activated carbon through scientific formula after post-treatment. Application of Medicinal Activated Carbon: Widely used in the pharmaceutical industry, fine chemical industry, etc
The biggest feature of medicinal activated carbon is its fast decolorization speed, strong adsorption capacity, developed internal pore structure, and large pores. It can effectively adsorb pigments in the medicine and reduce impurities without affecting the concentration and medicinal properties of other components in the medicine.
Removing pyrogen from activated carbon during drug preparation is a major challenge in the field of biotechnology today. It is particularly important to avoid pyrogen contamination and remove pyrogen during production. If intermediate or finished products are found to be contaminated with pyrogen, corresponding measures should be taken to remove it, but it should not affect the biological activity and yield of the products. Activated carbon adsorption was used to remove pyrogen from tetanus antitoxin products. The experimental results showed that this method is fast and simple to operate, and has a significant and repeatable adsorption effect on pyrogen in the products. After adsorption, the appearance of the products was further improved.
During the heating and extraction process of polysaccharides using activated carbon, sucrose and other substances undergo caramelization, forming pigments that deepen the color of the extract and affect the quality of the polysaccharides. There are many methods to remove the color of polysaccharides, but the most commonly used in industry is activated carbon.
The main function of pharmaceutical activated carbon is to remove black, red, brown, yellow, light yellow, pyrogen, etc. Black, brown, and red indicate that the removed impurities have a relatively large molecular weight and require activated carbon to have more large pores. If it is to remove yellow, light yellow, pyrogen, etc., activated carbon with a larger surface area is needed.
Because activated carbon can also dissolve impurities and contaminate products during decolorization, if customers are familiar with their products, we can choose activated carbon with lower iron content and higher activity to reduce the amount of activated carbon added and minimize the leaching of iron ions.
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